Dr. Urmi Bajpai

Dr. Urmi Bajpai is the founder teacher in-charge of the department, introduced by the University at ANDC in 1999. Her vision and hard work has richly contributed in shaping of B.Sc.(Hons) Biomedical Science course. Her focus is on giving hands on training to the students and make them independent learner. She is the pioneer of the Undergraduate research program in the college and has trained more than a hundred students. She has been sanctioned four research projects so far with a total grant of Rs. 77 Lakhs and has established a well-equipped and modern molecular biology research laboratory. She is recognized by the University as PhD guide. She is invited as a speaker in various national and international platforms on new models of education.

Title Dr. First Name Urmi Last Name Bajpai Photograph
Designation Associate Professor
Department Biomedical Sciences

Address
(Campus)

Acharya Narendra Dev College
Govind Puri, Kalkaji
New Delhi-110019.

Phone Number
(Campus)

 011-26412547

Fax

 011-26294540

Email

 urmi_bajpal@yahoo.com
Online Articles

 http://www.indiabioscience.org/node/38

 http://www.indiabioscience.org/blogs/practical-record-book-undergraduate-science-students

Education Subject Institution
 M.Sc.   Biosciences  Jamia Milia Islamia University
 Ph.D.  Microbiology   University of Delhi
Research Interests/ Specialization
  1. Facilitation of research at undergraduate level. More than a hundred and fifteen students of B.Sc. (Hons) Biomedical Science have undertaken research projects in her lab.
  2. New drug targets in Mycobacterium tuberculosis: Cloning and expression of select M.tuberculosis genes and purification of the recombinant proteins.
  3. Studying the potential of Mycobacterium tuberculosis Mur Pathway enzymes as potential targets for developing drugs against the pathogen.
  4.  Exploring Mycobacteriophages: genomic diversity and identification & characterization of proteins involved in the lysis of bacteria.
  5. She is one of the six coordinators from across the country for granting fellowships to deserving candidates (undergraduates, postgraduates, PhD scholars, postdoctoral fellows) and one of the five coordinators for granting fellowship to women scientists who wish to work with OSDD community and contribute in ongoing research on finding new drugs for Tuberculosis (TB).
Teaching Experience
Teaching experience: 15 years. Subjects taught: Bioorganic Chemistry, Biochemistry, Microbiology, Clinical Biochemistry and Medical Biotechnology
Research/ Academic Projects

Completed research project (funded by external agencies) as the Principal Investigator:

  1. A virtual centre of excellence in co-ordinated research on tuberculosis: development of alternate strartegies” in the college. Project was funded by the Department of Biotechnology (DBT), Govt. of India and was a component of a multi-institutional project carried out under the leadership of Dr. KanuryRao (International Centre for Genetic Engineering and Biotechnology). The project aimed towards generating a repository of about fifty clones in a suitable vector, each containing a gene of M. tuberculosis. The clones generated in this project are meant to be used in work leading to diagnostics, drug development, or developing immune reagents. The idea behind carrying out this component was to initiate college students into research. The grant received: Rs. 24.85 Lakhs. (July 2006-March 2009).
  2. CSIR - Open Source Drug Discovery Project ‘Cloning and expression of Mycobacterium tuberculosis genes’ in the college. The objective of the project is to look for new drug targets for Mycobacterium tuberculosis. A Select number of genes (20) have been cloned and expressed in a suitable host and are being tested for their potential to serve as drug targets. The grant received is Rs. 16.85 lakhs (July 2010- October 2012)
    In these two projects and in summer project on Mycobacteriophages, so far about hundred and fifteen students of B.Sc. (Hons) Biomedical Science have participated and developed a repository of Mtb gene clones (75) and recombinant proteins (15) and isolated (11) and purified (7) Mycobacteriophages.

Current projects (funded by external agencies and University of Delhi)

  1. She is the Principal Investigator of the CSIR - Open Source Drug Discovery Project ‘Mtb Mur pathway enzymes: Potential candidates for multi-targeted therapy’. It is also a multi-institutional project, a part of OSDD. Through this project, new drugs for Tuberculosis are being identified. Total research grant is Rs. 30.38 lakhs (March 2013- March 2015)
  2. She has been sanctioned Innovative Project by University of Delhi in 2013. The title is “Potential of Mobile healthcare in India, a feasibility study". Total research grant: Rs. 5 Lakhs

Other research activities:

  1. Summer Project in 2008: “Polymorphism in CYP1A in humans”. Here the polymorphism in the promoter region of CYP1A gene was investigated to assess its potential as biomarker for stones in Gall bladder and carcinoma of Gall bladder. 
  2. Summer Project in 2012: Guided three students in a study on “Antimicrobial effect of nano-particles”. The Nano sized ZnO particles were synthesized in the department of Physics, University of Delhi under the supervision of Prof Vinay Gupta. In her lab, students learnt to examine the antimicrobial effects (by disc-diffusion and broth method) of nano-particles.
  3. In June 2013 (as part of the ELITE research fellowship, sponsored by the college), nine students of B.Sc. (H) Biomedical Science participated in a new project on Phage hunting. Co-PI was Dr. Abhishek Mehta. In this project, students have discovered (11) and purified (7) Myobacteriophages from the environmental samples. Seven of these phages have been deposited in the international database for the Mycobacteriophages, maintained by the University of Pittsburgh. Further, a comparative study on lytic proteins from these Mycobacteriophages is being done.

 

Publications (Last Five Years)
In Indexed/Peer Reviewed Journals

Year of Publication

Title

Journal

Co-author/s

2013 Cloning, Expression, Purification and Bioinformatic analysis of 2-Methylcitrate Synthase from Mycobacterium tuberculosis Asian Pacific Journal of Tropical Medicine Sharma, R., Kausar T., Dattagupta, S., Chattopadhayay, T.K., Ralhan, R.
2008 Clinical significance of 14-3-3 zeta in human esophageal cancer" International Journal of Biological Markers Sharma, R., Kausar T., Dattagupta, S., Chattopadhayay, T.K., Ralhan, R.
Participation in Corporate Life

i. She has been in-charge and members of various committees in the past years. In charge of: Multi media committee (2004-2005), Faculty enrichment committee (2003-2004), Debating Society (2002-2003), Placement committee (2013-2014); and Member of : Alumni Committee and Career counseling and personality Development committee (2010), Electronics group (2006-2007), Environment club (2006-2007), College Fest organizing committee (2005-2006)

ii. Been the convener/coordinator of two committee setup for developing proposals for infrastructure development projects in the college.

iii.Arranged an interactive session by Prof. Graham Hatfull (pioneer on Mycobacteriophages), University of Pittsburgh, USA by Skype-Videoconference for the summer trainees working on phage discovery program in her lab in the college. Participating students have also contributed to the international database maintained by the University of Pittsburgh. She attended a week-long workshop in Pittsburgh and have been able to successfully complete a pilot study and trained students as well.

Workshops/Course Conducted/Participated

Workshops conducted:

  1. Coordinated a video-conference based short-term course (2 March-20 April 2013) on “Genomics, Proteomics and Bioethics” for the B.Sc. (Hons) Biomedical Science of the college with Ohio State University (USA) and Anna University (India).
  2. Faculty coordinator from the college for the projects on Annotation of Mycobacterium   tuberculosis and zebra fish, which students carried out under the guidance of the scientists from Institute of Genomics and Integrative Biology (IGIB), Delhi.
  3. Organizing member of the National Symposium on Biotechnology, orgainized by the college, November 2003.
  4. One of the three coordinators of a three day workshop on “Biotechnology”, organized by ANDC and Institute of Life Long learning (ILLL) for the teachers of University of Delhi, (October, 2008).
  5. Resource person in a five-day workshop on Science Education organized at ANDC in May 2012.
  6. Coordinated  a presentation by Dr. Karen Dell (University of California,USA), editor of educational project:
  7.  'i-Biology.org' for teachers and Ph.D scholars at ILLL, South Campus, where the usefulness of the site for educationists, particularly for biologists was explained.

Participated in:

  1. A two-week long international workshop on “Protein-Protein interactions”, organized by ICGEB, New Delhi, Nov 2005.
  2. A two-week long international workshop on “Host-Pathogen interactions”, organized by ICGEB, New Delhi, Nov 2006.
  3. The 4th Winter School in Immunology (a teaching-cum discussion course that brings all students of Immunology up to date with the current concepts) held in August, 2008 in Cochin. 
  4. National symposium on the “Role of chemistry in biology”, organized by the ANDC on 12-13 February, 2010.
  5. Howard Hughes Medical Institute/National Academies of Science North Star Summer Institutes for Undergraduate Science Education from June 11-16, 2012 at the University of Minnesota, Twin cities, USA.
  6. HHMI sponsored Phage hunting Workshop organized by the University of Pittsburgh, USA from June 25-29, 2012.
  7. Hands-on training on Protein Purification techniques in the Department of Biochemistry at Ohio State Univeristy, Columbus, USA, from 30 June to 7 July, 2012.
  8. TB meet organized by IISC and  OSDD at IISc, Bangalore (18-20 July, 2013)
Other Academic Contributions

i. Actively involved in revising the curriculum for B.Sc. (Hons.) Biomedical Sciences.  Has revised the subjects that she teaches as well has given inputs for other subjects such as cell biology, genetics, microbiology and immunology and Intellectual Property Rights (IPR in biology).

ii. Routinely invite eminent scientists in the department (in the capacity of teacher or teacher-in-charge). Prof. GP Talwar (TRF), Dr. Kanury Rao and Dr. Sunil Lal (ICGEB), Dr. R. Bamezai, Prof. Ram Ramaswami, Prof. Rakesh Bhatnagar  Dr. Andrew Lynn, Dr. Devapriya Choudhry, Dr. Rajiv Bhat (JNU),  Dr. Arif Ali (JMI), Dr. Dinakar Salunke, Dr. Sushanshu Vrati, Dr. Satyajit Rath and Dr. Vineeta Bal (NII), Dr.Aditya Mittal (IIT), Dr. Ramchandran, Dr. Rajesh Gokhale (IGIB) and Dr. Narayansami (TCGA) have visited the department and given talks on their subjects of specialization. This enables students to get wider perspective on various subjects and stay abreast of the latest developments in biomedical sciences and related areas. 

iii. She has placed BMS students for conducting summer research projects in the various institutes and universities, such as NII, ICGEB, JNU, TRF, BISR (Jaipur), IIT Delhi, TERI, NIB (Noida), Ranbaxy, Dabur, Panacea Biotech, NIH etc.

iv.She has been invited as speaker at various national and international platforms:

  • Received UGC travel grant to present her work on "impact assessment of undergraduate research experience" in June 2012 at a conference (SABER) on Science Education held at the University of Minnesota.
  • Was the invited speaker to give a talk on "Undergraduate research: relevance, scope and challenges" at the Centre for Life science Education (CLSE), Ohio State University, USA (July 2012).
  • Was the keynote speaker in the international conference, “Young Investigator Meeting” (YIM, a congregation of Postdoctoral fellows and young faculty from across the world) held at Jodhpur (February 2013). The theme of the conference was “Integration of Education and Research.” She was also the co-panelist with distinguished invitees from various National and International Institutes on discussion on topics such as “how to be a successful teacher”, “challenges in writing grants and "setting up of laboratories”, “science and women” etc
  • She gave a talk on ‘OSDD experience with the undergraduate student’, at a one-day workshop on Open Science by Creative Commons in October 2013 at University of Delhi, South Campus.
Membership        
  1.  Course committee for Biomedical Science
  2. Department Research Committee (DRC) in the University since 2008.
  3. Open Source Drug Discovery (OSDD), a CSIR Team India Consortium with Global Partnership with a vision to provide affordable healthcare to the developing world. This initiative has been taken to provide a platform where the scientists from across the world can collaborate & collectively endeavor towards the conquest of Tuberculosis.