Dr. Urmi Bajpai

Dr. Urmi Bajpai (DHE Meritorious teacher awardee-2014, recognized by the University as PhD guide) is the founder teacher in-charge of the department, introduced by the University at ANDC in 1999. Her vision and hard work has richly contributed in shaping of B.Sc. (Hons) Biomedical Science course. Her focus is on giving hands on training to the students and make them independent learner. She is the pioneer of the Undergraduate research program in the college and has trained more than a hundred students. She has been sanctioned four research projects so far with a total grant of Rs. 85 Lakhs and has established a well-equipped and modern molecular biology research laboratory. She is invited as a speaker in various national and international platforms on new models of education.

Title

Dr

First Name

Urmi

Last Name

Bajpai

Photograph

Designation

Associate Professor



Address

 

Phone No    Office

011-26412547011-26412547 

                     Residence

 

                      Mobile

 

Email

urmibajpai@andc.du.ac.in

Web-Page

https://sites.google.com/site/urmibajpailab

Educational Qualifications

Degree

Institution

Year

B.Sc (Physics, Chemistry, Biology)

DSC, University of Delhi

1990

M.Sc. (Biosciences)

Jamia Milia Islamia University, Delhi

1992

Ph.D. (Microbiology) 

University of Delhi

1997

Career Profile

  • Teaching since July, 1998  
  • Associate Professor (2009)

 

Administrative Assignments

Convenorship

  •  Rejuvenation of Research and Innovation committee (2015-) 
  •  Convener of placement committee (2012-2013) 
  •  12-member committee, responsible for drafting the proposal for the Advanced Central Instrumentation Facility for Life sciences and Physical Sciences (2012). 
  • Convener of Multimedia committee (2004-2005) 
  •  Faculty enrichment committee (2003-2004). 
  •  Debating Society (2002-2003).

 Member of

  •  Deputy Superintendent, Examinations (2014-2016) 
  • Fellowship Committee (2012-2014)
  • Alumni Committee (2010-2012, 2014-2016)
  • Purchase committee (2008-2010)
  • Electronic group (2006-2007)
  • Environment club (2006-2007)
  • College festival (2005-2006, 2010-2012)
  • Magazine committee (2004-2005)

 

Areas of Interest / Specialization

  1. Facilitation of research at undergraduate level. More than 150 students of B.Sc. (Hons) Biomedical Science have undertaken research projects in her lab.
  2. New drug targets in Mycobacterium tuberculosis: Cloning and expression of select M.tuberculosis genes and purification of the recombinant proteins.
  3. Studying the potential of Mycobacterium tuberculosis Mur Pathway enzymes as potential targets for developing drugs against the pathogen.
  4. Exploring Mycobacteriophages: genomic diversity and identification & characterization of proteins involved in the lysis of bacteria. (TCOF Projects)

 

Subjects Taught 

  • Bioorganic Chemistry
  • Biochemistry
  • Microbiology
  • Clinical Biochemistry
  • Medical Biotechnology

Research Guidance

Recognized by the university of Delhi as a PhD guide. One student is registered for PhD program. He is working on the research project from OSDD, titled “Potential of Mur pathway enzymes as multi-target anti-TB drug therapy”, sanctioned by CSIR.

No of Ph.D. Students : 01

No of TATA CSIR-OSDD Fellow : 05

 

Publications Profile

 

S.no

Year of publication

Title

Journal

Co-authors

1

2015

A comparative molecular dynamics study of MurA enzymes from E. coli and M. tuberculosis

Innovations in Pharmaceuticals and Pharmacotherapy  

Shahzaib Ahamad, Faez Iqbal Khan, Urmi Bajpai, Shahnawaz Ali, Neerja Dwivedi and Md. Imtaiyaz Hassan

2

2015

Functional analysis of TPM domain containing Rv2345 of Mycobacterium tuberculosis identifies its phosphatase activity.

Protein expression and purification  

Avni Sinha, Kandasamy Eniyan, Swati Sinha, Andrew M Lynn, Urmi Bajpai

3

2015

Building a repository of potential drug targets in Mycobacterium tuberculosis by crowdsourcing.

DU Journal of Undergraduate Research and Innovation

Aamod Utpal, Abhinav Tyagi, Akhilesh Kumar, Amit Gaurav, Amrita Singh, Atul Kumar Tiwari, Avantika Singh, Beneeta Kalha, Bharat Bhatt, Bimlesh Yadav, Deepika Kumari, Harsha Rohira, Himanshu Bhatt, Kamlesh Kumari, Kartika Vashistha, Karuna Singh, Khairun Nisaa, Mohit Kumar, Navbhar Sharma, Preeti Yadav, Rajat Sharma, Ritu Arora, Ruchika Pokhriyal, Shahbaz Siddiqui, Sneha Mishra, Sonal Kapur, Srishti Nanda, Sumit Kinger, Sweety Raj, Vartika Channa, Vivek Bhardwaj, Kandasamy Eniyan and Urmi Bajpai

4

2015

Structure based virtual screening to identify inhibitors against MurE Enzyme of Mycobacterium tuberculosis using AutoDock Vina.

Bioinformation

Shilipi Singh, Urmi Bajpai, and Andrew Michael Lynn

5

2015

Cloning, Expression, Purification and Bioinformatic analysis of 2-Methylcitrate Synthase from Mycobacterium tuberculosis

Asian Pacific Journal of Tropical Medicine

Kandasamy Eniyan and Urmi Bajpai

6

2008

Clinical significance of 14- 3-3 zeta in human esophageal cancer.

International Journal of Biological Markers

Urmi Bajpai, Rinu Sharma, Siddharth Dutta Gupta, Ranju Ralhan

7

1998

Mineralization of (C14) octadecane by Acinetobacter calcoaceticus S19. 

Canadian Journal of Microbiology

Bajpai, U., Kuhad, R. C. and Khanna, S.

 

Conference Organization/ Presentations (in the last three years)

 

Invited Lectures in the last three years: 

  1. “Learning science through research and new teaching methodologies” at a 2-days meet on Teaching of the sciences in higher education: Issues and Challenges in Pedagogy and Research (2016, 27 – 28th May, Bangalore University).
  2. "Crowdsourcing in wet labs with undergraduates" at the Open Source Pharma (OSP), organized by Rockfellar Foundation at the Belllagio Centre, Italy (16-18 July, 2014).
  3. “Open science: Shared gains by the educator and the leaner” at a Workshop on Open Science for Higher Education and Research ( 3 October, 2013, University of Delhi, South Campus)
  4. Keynote speaker by Young India Investigator (YIM 2013, 9-14th February, Jodhpur, India). The theme was integration of education and research.

 

Participation in Seminars/ Symposium in last one year

  1. Indo-German seminar on Modeling Chemical and Biological (Re) activity - MCBR at IIT Delhi on 7th November 2015.
  2. Review meeting of national committee of TATA CSIR-OSDD fellowships at ANDC on 6th November 2015
  3. Presentation of OSDD project report during annual review meeting at CSIR headquarters (15-16 September, 2015)
  4. Tenth Annual Symposium on Frontiers in Biomedical Research (October 29-31, 2015)
  5. A brainstorming meeting (16-18 July, 2014) on Open Source Pharma, organized by Rockfellar Foundation at the Belllagio Centre, Italy.

 

Research Projects (Major Grants/Research Collaboration)

 

S.no

Title

Funding agency

Amount sanctioned

( in Lakhs)

Status

1

Development of alternative anti-bacterials through Bacteriophage-derived proteins, isolated from India. 

DST-IEDC

01

Ongoing

One year (2015 to 2016) 

2

Mtb Mur pathway enzymes: Potential targets for Multi-targeted therapy”

(Screening of chemical libraries using one-pot assay developed for Mur enzymes of Mycobacterium tuberculosis)

 

CSIR-OSDD

7.184

Completed

6 months (October 2015 to March 2016) 

3

Mtb Mur pathway enzymes: Potential targets for Multi-targeted therapy 

CSIR-OSDD

30.38

Completed

Two years (2013-2015) 

4

Mobile healthcare: The future of health management in India- A Feasibility Study

DU – innovation project

5

Completed

One year (2013-2014)

5

Cloning and Expression of Mycobacterium tuberculosis genes

CSIR-OSDD

16.85

Completed

Two years (2010-2012)

6

A virtual centre of excellence in coordinated research on tuberculosis: Development of alternate strategies

DBT

24.85

Completed

Three years (2006 -2009)

 

RESEARCH OUTPUTS

 

Repositories built by undergraduate students:

 

  • Repository of Mycobacterium tuberculosis genes : 70
  • Repository of Mycobacterium tuberculosis proteins : 15
  • No. of Mycobacteriophages discovered and deposited in the Actinobacteriophage database   (phagesdb.org), University of Pittsburgh, USA: 21
  • No. of phage whole genomes sequenced: 07
  • No of genomes submitted in NCBI genbank: 02

 

Awards and Distinctions

 

  • Selected for Delhi Government’s meritorious teacher’s Award in 2014, which includes a citation and a cash prize of Rs. One Lakh.
  • National coordinator for TATA CSIR-OSDD FELLOWSHIP PROGRAMME

 

Association With Professional Bodies

     

  • Member Open Source Drug Discovery (2009 – 2016)
  • Member Open source pharma (2014 onwards)

 

Other Activities

  1. Invited to give a talk on “Undergraduate research: relevance, scope and challenges” at the Centre for Life Science Education (CLSE), Ohio State University, Columbus, USA on 9 July 2012. The audiences were the teaching and administrative staff of CLSE.
  2. Invited for poster presentation at the Society for the Advanced Biology Education Research (SABER July 12-15, 2012) at the University of Minnesota, USA on the topic “Independent Research Opportunities for the Undergraduates: Building of a repository of genes of Mycobacterium tuberculosis cloned in a suitable vector”.
  3. Participated in Howard Hughes Medical Institute/National Academies of Science North Star Summer Institutes for Undergraduate Science Education from June 11-16, 2012 at the University of Minnesota, Twin cities, USA.
  4. Participated in HHMI sponsored Phage hunting Workshop organized by the University of Pittsburgh, USA from June 25-29, 2012.
  5. Got hands-on training on Protein Purification techniques in the Department of Biochemistry at Ohio State University, Columbus, USA, from 30 June to 7 July 2012.
  6. Have coordinated videoconference based short-term course for the B.Sc. (Hons) Biomedical Science with Ohio State University (USA) and Anna University (India).
  7. Participated in TB meet organized by IISc and OSDD at IISc, Bangalore (18-20 July)